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KMID : 0357520080310030259
Journal of Radiological Science and Technology
2008 Volume.31 No. 3 p.259 ~ p.266
Association of Bone Mineral Density with the Metabolic Syndrome
Kang Young-Han

Kam Shin
Abstract
Objective : The purpose of this study was to examine the relationship between bone mineral density (BMD) and the metabolic syndrome.

Method: We conducted a cross-sectional study of 1204 adults(males: 364 females: 840) in a general hospital health promotion center. They were grouped into the normal and lower BMD group according to bone loss(osteopenia, osteoporosis), as determined by duel energy X-ray absorptiometery(DEXA). We analyzed the association between BMD and metabolic syndrome by multiple logistic regression analysis. After adjustment for age, weight, alcohol intake, smoking, regular exercise, regular intake of meals, and menopausal status, odds ratios for the prevalence of the metabolic syndrome by gender were calculated for lower BMD.

Results: After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with bone loss in men(p<0.001). If the odds ratio of normal group is 1.00, then that of the lower BMD group is 3.07(95% CI=1.83-5.16). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome was significantly decreased in High BMI, Low HDL in men and in High BMI in women(p<0.05).

Conclusions : This study shows that BMD was associated with metabolic syndrome. Further studies needed to obtain evidence concerning the association between BMD and metabolic syndrome.
KEYWORD
Bone mineral density, Metabolic syndrome, Cross-sectional study
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